Press reviews
HIV remains a major global challenge, with more than 1.3 million new infections recorded in 2024, particularly affecting marginalized populations. Although oral pre-exposure prophylaxis (PrEP) has proven effective, its real-world impact is limited by adherence barriers such as stigma, daily pill fatigue, and inconsist...
Human Immunodeficiency Virus (HIV) remains a major public health issue, especially in high-prevalence countries where it continues to cause substantial morbidity and mortality. Young people—particularly young women—represent an especially vulnerable population. They often struggle to access appropriate health services...
Chronic HIV infection, even when well controlled by antiretroviral therapy, is associated with an increased cardiometabolic risk, including higher rates of cardiovascular events, hypertension, insulin resistance, and dyslipidemia. This elevated risk cannot be explained solely by traditional factors, but also by persis...
Metastatic testicular germ cell tumors (TGCTs) currently achieve high cure rates with cisplatin-based chemotherapy; however, 20–30% of patients relapse or exhibit resistance to first-line treatment. For those facing refractory or relapsed disease, the identification of prognostic and predictive biomarkers is becoming es...
2025-11-28
Testicular Germ Cell Tumors: epidemiology, risk factors, and advances in management
Oncology
Testicular germ cell tumors (TGCTs) represent the most common malignancy in young men aged 15–40 years, accounting for approximately 95% of all testicular cancers. They arise from germ cells and are classified as seminomas or non-seminomatous tumors (NSGCTs), each requiring distinct treatment strategies.
Despit...
Metastatic hormone-sensitive prostate cancer (mHSPC) is an advanced stage of the disease, with a prognosis that remains concerning despite recent therapeutic advances. Standard treatment is based on androgen deprivation therapy (ADT), to which agents such as docetaxel or androgen receptor–targeted therapies (ARATs)—inc...
Testicular cancer is the most common solid tumor in young men and carries an excellent prognosis thanks to current treatments such as surgery, chemotherapy, and radiotherapy. However, fertility preservation remains a major concern, as these treatments can impair spermatogenesis, either temporarily or permanently. &n...
Metastatic castration-resistant prostate cancer (mCRPC) represents an advanced and aggressive stage of the disease in which tumor cells continue to progress despite androgen suppression. It is characterized in most cases by bone metastases, which are responsible for considerable morbidity and increased mortality. These...
Cancer treatment, whether based on chemotherapy, radiotherapy, or immunotherapy, is frequently associated with gastrointestinal side effects. These digestive symptoms have a direct impact on patients’ nutritional status and may compromise the effectiveness of oncological treatments.
Convention...
2025-11-24
Does smoking during pregnancy protect against type 1 diabetes?
Endocrinology and Metabolism
Type 1 diabetes (T1D) is a chronic autoimmune disease caused by the destruction of the β-cells of the pancreatic islets of Langerhans, leading to lifelong dependence on insulin. Its global prevalence is steadily increasing, particularly in developed countries, making T1D a major public health concern due to its m...
2025-11-24
Urology-nephrology Oncology
Radical prostatectomy (RP) remains a key treatment for men with localized prostate cancer. However, it is associated with two major side effects: urinary incontinence and erectile dysfunction, both of which significantly affect postoperative quality of life. Nerve-sparing (NS) techniques allow partial preservation of erec...
2025-11-21
Prostate cancer: could physical exercise be the key to regaining an active sexual life?
Urology-nephrology Oncology
Sexual dysfunction is a common side effect of prostate cancer treatments, impacting patients’ quality of life well beyond the acute phase of disease. Despite pharmacological progress, current therapeutic approaches often fail to sufficiently address the physical, psychological, and relational components involved. This hig...
2025-11-20
Prostatectomy or SBRT: which treatment better preserves quality of life?
Urology-nephrology Oncology
In men with localized prostate cancer at low or intermediate risk, two curative treatments are now standard options: radical prostatectomy and stereotactic body radiotherapy (SBRT). While surgery is often regarded as the more radical approach, radiotherapy is considered less invasive, but its side effects—particularly bo...
The digital rectal exam (DRE) has historically been a key tool in the early detection of prostate cancer (PCa). Before the widespread use of prostate-specific antigen (PSA) testing, DRE was the primary method for identifying potentially aggressive tumors. PSA transformed early detection by identifying cancers even in asy...
2025-11-19
Oncology
Metastatic castration-resistant prostate cancer (mCRPC) represents an advanced stage of the disease, commonly treated with androgen deprivation therapy (ADT). Although this strategy improves survival, it often leads to a deterioration in quality of life (QoL), with side effects such as fatigue, cognitive impairment, bone...